Natural products and their derivatives have been shown to be effective drug candidates against various diseases for many years.Over a long period of time, nature has produced an abundant and prosperous source pool for novel therapeutic agents with distinctive structures.Major natural-product-based drugs approved for clinical use include anti-infect
Was the African American Great Migration Delayed by Outlawing Emigrant Agents?
The question of why the Great Migration from the South did not begin before the 1910s remains open.The empirical significance of laws outlawing emigrant agents, who could have helped African Americans migrate, has not previously Lencería been considered.We analyze two natural experiments whereby one state had a law but its neighbor did not.We fail
Planting the seeds for a forest of RNAi pathways
Cells from most eukaryotic species make several different types of small interfering Lencería RNAs.Pioneering work in plants, published in PLOS Biology almost 20 years ago, established a framework to understand how multiple RNA interference pathways can regulate the genome in parallel.This Perspective looks back at a classic PLOS Biology paper tha
Comparative Analysis of Pixel-Level Fusion Algorithms and a New High-Resolution Dataset for SAR and Optical Image Fusion
Synthetic aperture radar (SAR) and optical images often present different geometric structures and texture features for the same ground object.Through the fusion of SAR and optical images, it can effectively integrate their complementary information, thus better meeting the requirements of remote sensing applications, such as target recognition, cl
Sensitivity enhancement of SPR based refractive index sensor in VIS-NIR region by using ZnS and PVP
A highly sensitive optical sensor is presented.This sensor is having multilayer structure that is designed and optimized theoretically by using Zinc Sulfide (ZnS) and Polyvinylpyrrolidone (PVP).The optical sensor proposed here is based on Surface Plasmon Resonance (SPR) technique by using Kretschmann configuration.This SPR sensor is designed with B